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The University of Tennessee

The Department of Mathematics

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Judy D. Day

Associate Professor
Department of Mathematics
Department of Electrical Engineering and Computer Science

Senior personnel, National Institute for Mathematical and Biological Synthesis (NIMBioS).

ORCID Profile:

Research Interests:

My current interests are motivated by the potential of mathematical and engineering techniques to assist in answering vital questions in the medical field. My main objective is to conduct research within an interdisciplinary group to promote a symbiotic relationship among the various areas of expertise to acquire results and develop tools of clinical relevance and academic significance.

My primary research is focused on the development and analysis of mathematical models relating to the immune response to various stimuli and the application of control methodologies to modulate the immune response withtherapeutic inputs.


  • Inflammation and disease: Modelling and modulation of the inflammatory response to alleviate critical illness

    A review/perspectives article published in Current Opinion in Systems Biology proposing a framework in which to achieve personalized therapeutic interventions for critical illness via model-based precision medicine.
  • Solving Immunology?

    A perspectives article published in Trends in Immunolgy that emerged from the National Institute of Allergy and Infectious Disease (NIAID) workshop "Complex Systems Science, Modeling and Immunity" and subsequent discussions regarding the potential synergy of high-throughput data acquisition, data-driven modeling, and mechanistic modeling to define new mechanisms of immunological disease and to accelerate the translation of these insights into therapies.
  • How does fever work? As a non-specific stressor

    Atlas of Science summary written by co-author Dr. Edmund K. LeGrand Summary Article
  • 11th Annual NIMBioS Undergraduate Research Conference at the Interface of Biology and Mathematics - Nov. 16-17, 2019

    Conference Page

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Contact Info:

Email Address:

Office Address:
211 Ayres Hall

Mailing Address:
Department of Mathematics
The University of Tennessee
227 Ayres Hall
1403 Circle Dr
Knoxville, TN 37996-1320

Phone and Fax Numbers:
Phone: (865) 974-8419
Fax: (865) 974-6576